As approximately 10 were detained in clashes one England fan has been injured.
England supporters hurled bottles while was returned by police in riot gear with stun grenades.
A pool of blood was left to the street.
He was spotted receiving therapy while some had been awakened one by one with hands behind their backs into a police van.
Police were unable to confirm the number of arrests have been made.
The ugly scenes erupted just before 7pm local time following an afternoon of drinking supporters who had descended on the city ahead of their groups European Qualifier from the Czech Republic.
Hundreds of fans took at the towns Old Town over a little square, chanting and singing.
There had been little problem, together with police participation to telling fans to remove flags restricted until night dropped.
However, since bottles were pelted at officials, a documented warning was played English warning them tocomply with the law and face coverings and pyrotechnics are illegal.
As missiles continued to be thrown czech police progressed, firing stun grenades as fans were forced back via a small archway.
About 10 men were pinned into a corner and made to lie down face, while another was spotted being hauled on the ground nearby as officers.
Even more are thought to have travelled Nearly 3,800 England fans bought tickets for Friday nights battle.
The overdue kick-off time of 8.45pm and the citys party standing contributed to fears of a repeat of ugly scenes observed on current trips to Amsterdam, Dortmund and Porto.
The fixture also coincided to the countrys most renowned singer and traveling fans are told to be respectful of mourners.
Ahead of the game, the Football Association asked fans toreport that fool should they see anti-social behaviour, while authorities urged those going to the game to notembarrass themselves.
Deputy chief constable Mark Roberts, the National Police Chiefs Councils football policing direct, stated Pragues a gorgeous city. Go, like it, it is an absolutely fantastic place. We have got a staff that is well worth celebrating and supporting so theres lots of stuff to go and revel in.
Just dont embarrass yourself or anybody else by drinking to excess and acting in a way where you can wind up on film or print the following moment.

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